Rubicon 抗体 (AA 859-972)
Quick Overview for Rubicon 抗体 (AA 859-972) (ABIN7193445)
抗原
See all Rubicon (KIAA0226) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 859-972
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原理
- RUBCN Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Rubicon (KIAA0226) (KIAA0226)
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别名
- RUBCN
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背景
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The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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分子量
- 108.6 kDa
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基因ID
- 9711
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UniProt
- Q92622
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途径
- Autophagy
抗原
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