SETD2 抗体 (AA 2054-2245)
Quick Overview for SETD2 抗体 (AA 2054-2245) (ABIN7193416)
抗原
See all SETD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2054-2245
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原理
- SETD2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SETD2 (SET Domain Containing 2 (SETD2))
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别名
- SETD2
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背景
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
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分子量
- 287.6 kDa
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途径
- Tube Formation
抗原
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