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XIAP 抗体 (AA 1-268)

This 小鼠 单克隆 anti-XIAP antibody (Clone 4C12G10) specifically detects XIAP in ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7193408
发货至: 中国
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Quick Overview for XIAP 抗体 (AA 1-268) (ABIN7193408)

抗原

See all XIAP 抗体
XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

  • 82
  • 45
  • 31
  • 3
  • 2
  • 1

宿主

  • 74
  • 12
  • 1
小鼠

克隆类型

  • 74
  • 11
单克隆

标记

  • 55
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This XIAP antibody is un-conjugated

应用范围

  • 73
  • 35
  • 26
  • 18
  • 15
  • 13
  • 13
  • 13
  • 9
  • 6
  • 3
  • 2
  • 2
ELISA, Flow Cytometry (FACS)

克隆位点

4C12G10
  • 抗原表位

    • 16
    • 12
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-268

    原理

    XIAP Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

    别名

    XIAP

    背景

    This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

    分子量

    56.7 kDa

    基因ID

    331

    UniProt

    P98170

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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