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TLR3 抗体 (AA 24-217)

This 小鼠 单克隆 anti-TLR3 antibody (Clone 6F3G4) specifically detects TLR3 in ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7193368
发货至: 中国
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Quick Overview for TLR3 抗体 (AA 24-217) (ABIN7193368)

抗原

See all TLR3 抗体
TLR3 (Toll-Like Receptor 3 (TLR3))

适用

  • 98
  • 72
  • 29
  • 6
  • 2
  • 1
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  • 1

宿主

  • 83
  • 31
  • 10
  • 4
  • 2
小鼠

克隆类型

  • 86
  • 44
单克隆

标记

  • 57
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  • 10
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  • 2
  • 1
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  • 1
  • 1
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This TLR3 antibody is un-conjugated

应用范围

  • 79
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  • 37
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  • 21
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  • 13
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  • 8
  • 5
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ELISA, Flow Cytometry (FACS)

克隆位点

6F3G4
  • 抗原表位

    • 16
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 1
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    AA 24-217

    原理

    CD283 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD283 (AA: 24-217) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    TLR3 (Toll-Like Receptor 3 (TLR3))

    别名

    CD283

    背景

    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]

    分子量

    103.8 kDa

    UniProt

    O15455

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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