CXCR2 抗体
Quick Overview for CXCR2 抗体 (ABIN7193274)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- CD182 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human CD182 expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 316-360) antibody
CXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (pSer347) antibodyCXCR2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibodyCXCR2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7E9H12 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-40) antibodyCXCR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) antibodyCXCR2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-57) antibodyCXCR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Extracellular Domain) antibodyCXCR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-30), (N-Term) antibodyCXCR2 适用: 人 WB, IHC, FACS 宿主: 兔 Chimeric SE2 unconjugated Recombinant Antibody
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibodyCXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 196-212), (Middle Region) antibodyCXCR2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
-
别名
- CD182
-
背景
-
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
-
分子量
- 40.8 kDa
-
基因ID
- 3579
-
UniProt
- P25025
-
途径
- cAMP Metabolic Process
抗原
-
