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CD46 抗体 (AA 35-179)

This anti-CD46 antibody is a 小鼠 单克隆 antibody detecting CD46 in WB, FACS, ELISA 和 ICC. Suitable for 人.
产品编号 ABIN7193209
发货至: 中国

Quick Overview for CD46 抗体 (AA 35-179) (ABIN7193209)

抗原

See all CD46 抗体
CD46

适用

  • 130
  • 37
  • 23
  • 11
  • 10
  • 3

宿主

  • 91
  • 62
  • 2
  • 1
小鼠

克隆类型

  • 78
  • 78
单克隆

标记

  • 63
  • 17
  • 14
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  • 4
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is un-conjugated

应用范围

  • 92
  • 86
  • 42
  • 41
  • 38
  • 23
  • 22
  • 14
  • 14
  • 9
  • 8
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

克隆位点

5A8C11
  • 抗原表位

    • 16
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-179

    原理

    CD46 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CD46

    别名

    CD46

    背景

    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

    分子量

    43.7 kDa

    基因ID

    4179

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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