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TYROBP 抗体

This anti-TYROBP antibody is a 兔 多克隆 antibody detecting TYROBP in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7192969
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TYROBP 抗体 (ABIN7192969)

抗原

See all TYROBP 抗体
TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This TYROBP antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 原理

    TYROBP Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of Human TYROBP

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

     pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

    别名

    TYROBP

    背景

    Background: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

    Aliases: DAP 12 antibody, DAP12 antibody, DNAX activation protein 12 antibody, DNAX-activation protein 12 antibody, KAR-associated protein antibody, KARAP antibody, Killer activating receptor associated protein antibody, Killer-activating receptor-associated protein antibody, PLOSL antibody, TYOBP_HUMAN antibody, TYRO protein tyrosine kinase binding protein antibody, TYRO protein tyrosine kinase-binding protein antibody, TYROBP antibody

    UniProt

    O43914
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