NCKAP1 抗体
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北京 101111
Quick Overview for NCKAP1 抗体 (ABIN7191586)
抗原
See all NCKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NCKAP1 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of Human NCKAP1
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亚型
- IgG
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anti-NCK Associated Protein 1 (NCKAP1) antibody
NCKAP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) antibodyNCKAP1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) (AA 1-250) antibodyNCKAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
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别名
- NCKAP1
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背景
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Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
Aliases: FLJ11291 antibody, KIAA0587 antibody, Membrane associated protein HEM2 antibody, Membrane-associated protein HEM-2 antibody, MGC8981 antibody, NAP 1 antibody, NAP1 antibody, NAP125 antibody, NCK associated protein 1 antibody, NCK associated protein antibody, Nck-associated protein 1 antibody, Nckap1 antibody, NCKP1_HUMAN antibody, OTTHUMP00000163460 antibody, OTTHUMP00000163461 antibody, p125Nap1 antibody
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UniProt
- Q9Y2A7
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途径
- RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
抗原
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