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NKX3-1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects NKX3-1 in IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7184486
发货至: 中国
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Quick Overview for NKX3-1 抗体 (N-Term) (ABIN7184486)

抗原

See all NKX3-1 抗体
NKX3-1 (NK3 Homeobox 1 (NKX3-1))

适用

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宿主

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  • 1

克隆类型

  • 61
  • 53
多克隆

标记

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This NKX3-1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    N-Term

    原理

    NKX3-1 Antibody

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from N-terminal of Human NKX3.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NKX3-1 (NK3 Homeobox 1 (NKX3-1))

    别名

    NKX3-1

    背景

    Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

    Cai Bowen, Cancer Res., Jan 2007, 67: 455 - 464.
    Xiang Li, Mol. Cell. Biol., Apr 2006, 26: 3008 - 3017.
    Ekatherine Asatiani, Cancer Res., Feb 2005, 65: 1164 - 1173.
    Carlise R. Bethel, Cancer Res., Nov 2006, 66: 10683 - 10690.

    Aliases: BAPX 2 antibody, BAPX2 antibody, Homeobox protein NK-3 homolog A antibody, Homeobox protein Nkx 3.1 antibody, Homeobox protein Nkx-3.1 antibody, Homeobox protein Nkx3.1 antibody, NK homeobox (Drosophila) family 3 A antibody, NK homeobox family 3 A antibody, NK homeobox, family 3, member A antibody, NK3 homeobox 1 antibody, NK3 transcription factor homolog A antibody, NK3 transcription factor related locus 1 antibody, NKX 3 antibody, Nkx 3.1 antibody, NKX 3A antibody, NKX3 1 antibody, NKX3 antibody, Nkx3-1 antibody, NKX3.1 antibody, Nkx3.1, mouse, homolog of antibody, NKX31_HUMAN antibody, NKX3A antibody

    UniProt

    Q99801

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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