NKX3-1 抗体 (N-Term)
Quick Overview for NKX3-1 抗体 (N-Term) (ABIN7184486)
抗原
See all NKX3-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from N-terminal of Human NKX3.
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亚型
- IgG
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应用备注
- IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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别名
- NKX3-1
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背景
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Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Cai Bowen, Cancer Res., Jan 2007, 67: 455 - 464.
Xiang Li, Mol. Cell. Biol., Apr 2006, 26: 3008 - 3017.
Ekatherine Asatiani, Cancer Res., Feb 2005, 65: 1164 - 1173.
Carlise R. Bethel, Cancer Res., Nov 2006, 66: 10683 - 10690.Aliases: BAPX 2 antibody, BAPX2 antibody, Homeobox protein NK-3 homolog A antibody, Homeobox protein Nkx 3.1 antibody, Homeobox protein Nkx-3.1 antibody, Homeobox protein Nkx3.1 antibody, NK homeobox (Drosophila) family 3 A antibody, NK homeobox family 3 A antibody, NK homeobox, family 3, member A antibody, NK3 homeobox 1 antibody, NK3 transcription factor homolog A antibody, NK3 transcription factor related locus 1 antibody, NKX 3 antibody, Nkx 3.1 antibody, NKX 3A antibody, NKX3 1 antibody, NKX3 antibody, Nkx3-1 antibody, NKX3.1 antibody, Nkx3.1, mouse, homolog of antibody, NKX31_HUMAN antibody, NKX3A antibody
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UniProt
- Q99801
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
抗原
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