KSR2 抗体
Quick Overview for KSR2 抗体 (ABIN7183716)
抗原
See all KSR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from internal of Human KSR2.
-
亚型
- IgG
-
-
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibody
KSR2 适用: 人 ELISA, WB, RNAi 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 6C9 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 159-296) antibodyKSR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Internal Region) antibodyKSR2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 603-638), (C-Term) antibodyKSR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB09886 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (C-Term) antibodyKSR2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (Ile694) antibodyKSR2 适用: 人, 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 411-500) antibodyKSR2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 6F12 unconjugated
anti-Kinase Suppressor of Ras 2 (KSR2) (AA 1-829) antibodyKSR2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB:1:500-1:3000, IF:1:100-1:500,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
-
别名
- KSR2
-
背景
-
Background:
Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Ota T., Nat. Genet. 36:40-45(2004).
Scherer S.E., Nature 440:346-351(2006).
Channavajhala P.L., J. Biol. Chem. 278:47089-47097(2003).Aliases: FLJ25965 antibody, hKSR 2 antibody, hKSR2 antibody, Kinase suppressor of Ras 2 antibody, KSR 2 antibody, Ksr2 antibody, KSR2_HUMAN antibody
-
UniProt
- Q6VAB6
抗原
-
