CIT 抗体
Quick Overview for CIT 抗体 (ABIN7183401)
抗原
See all CIT 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human CTRO.
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亚型
- IgG
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anti-Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) (AA 1928-2027) antibody
CIT 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT) (AA 1000-1300) antibodyCIT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))
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别名
- CIT
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背景
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Background: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Nagase T., DNA Res. 6:63-70(1999).
Scherer S.E., Nature 440:346-351(2006).
Gruneberg U., J. Cell Biol. 172:363-372(2006).Aliases: CIT antibody, CRIK antibody, KIAA0949 antibody, STK21Citron Rho-interacting kinase antibody, CRIK antibody, EC 2.7.11.1 antibody, Serine/threonine-protein kinase 21 antibody
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UniProt
- O14578
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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