ADRA2B 抗体
Quick Overview for ADRA2B 抗体 (ABIN7183076)
抗原
See all ADRA2B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human Adrenergic Receptor alpha-2B.
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亚型
- IgG
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应用备注
- IF:1:100-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))
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别名
- ADRA2B
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背景
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Background: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).
Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).
Small K.M., J. Biol. Chem. 276:4917-4922(2001).Aliases: ADRA2B antibody, ADRA2L1 antibody, ADRA2RL1Alpha-2B adrenergic receptor antibody, Alpha-2 adrenergic receptor subtype C2 antibody, Alpha-2B adrenoreceptor antibody, Alpha-2B adrenoceptor antibody, Alpha-2BAR antibody
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UniProt
- P18089
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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