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UBE2D2 抗体 (C-Term)

This anti-UBE2D2 antibody is a 兔 多克隆 antibody detecting UBE2D2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7180280
发货至: 中国

Quick Overview for UBE2D2 抗体 (C-Term) (ABIN7180280)

抗原

See all UBE2D2 抗体
UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBE2D2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    交叉反应

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from C-terminal of Human UBE2D2.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

    别名

    UBE2D2

    背景

    Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

    Jensen J.P., J. Biol. Chem. 270:30408-30414(1995).
    Rolfe M., Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995).
    Guinn B.-A., Biochem. Biophys. Res. Commun. 335:1293-1304(2005).

    Aliases: E2(17)KB2 antibody, OTTHUMP00000223475 antibody, OTTHUMP00000223476 antibody, OTTHUMP00000223477 antibody, OTTHUMP00000223478 antibody, OTTHUMP00000224375 antibody, PUBC 1 antibody, PUBC1 antibody, UB2D2_HUMAN antibody, UBC 4 antibody, UBC 4/5 antibody, UBC4 antibody, UBC4/5 antibody, UBC4/5 homolog yeast antibody, UBCH 5B antibody, UBCH5B antibody, UBE2D2 antibody, Ubiquitin carrier protein antibody, Ubiquitin carrier protein D2 antibody, Ubiquitin conjugating enzyme E2 17 kDa 2 antibody, Ubiquitin conjugating enzyme E2 D2 antibody, Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5) antibody, Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast) antibody, Ubiquitin conjugating enzyme E2D 2 antibody, Ubiquitin protein ligase D2 antibody, Ubiquitin-conjugating enzyme E2 D2 antibody, Ubiquitin-conjugating enzyme E2(17)KB 2 antibody, Ubiquitin-conjugating enzyme E2-17 kDa 2 antibody, Ubiquitin-protein ligase D2 antibody

    UniProt

    P62837

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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