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UBE2D2 抗体 (Middle Region)

UBE2D2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775673
发货至: 中国
  • 抗原 See all UBE2D2 抗体
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    抗原表位
    • 15
    • 12
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 59
    • 30
    • 14
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼
    宿主
    • 52
    • 7
    克隆类型
    • 53
    • 6
    多克隆
    标记
    • 31
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2D2 antibody is un-conjugated
    应用范围
    • 53
    • 27
    • 13
    • 13
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UBE2D2
    Top Product
    Discover our top product UBE2D2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 547 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Desforges, Lacey, Glazier, Greenwood, Mynett, Speake, Sibley: "SNAT4 isoform of system A amino acid transporter is expressed in human placenta." in: American journal of physiology. Cell physiology, Vol. 290, Issue 1, pp. C305-12, (2005) (PubMed).

  • 抗原
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    别名
    UBE2D2 (UBE2D2 产品)
    别名
    E2(17)KB2 antibody, PUBC1 antibody, UBC4 antibody, UBC4/5 antibody, UBCH5B antibody, 1500034D03Rik antibody, Ubc2e antibody, Ube2d2 antibody, ubc4 antibody, ube2d2 antibody, zgc:55886 antibody, E217kB antibody, ubiquitin conjugating enzyme E2 D2 antibody, ubiquitin-conjugating enzyme E2D 2A antibody, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) antibody, ubiquitin-conjugating enzyme E2D 2 antibody, ubiquitin conjugating enzyme E2 D3 antibody, UBE2D2 antibody, Ube2d2a antibody, ube2d2 antibody, Ube2d2 antibody, UBE2D3 antibody
    背景
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001).[supplied by OMIM].
    Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
    Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
    Protein Size: 547
    分子量
    60 kDa
    基因ID
    7322
    NCBI登录号
    NM_018018, NP_003330
    UniProt
    P62837
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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