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EPH Receptor B2 抗体 (C-Term)

This anti-EPH Receptor B2 antibody is a 兔 多克隆 antibody detecting EPH Receptor B2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7180167
发货至: 中国

Quick Overview for EPH Receptor B2 抗体 (C-Term) (ABIN7180167)

抗原

See all EPH Receptor B2 (EPHB2) 抗体
EPH Receptor B2 (EPHB2)

适用

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宿主

  • 48
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克隆类型

  • 50
  • 20
多克隆

标记

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This EPH Receptor B2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    交叉反应

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from C-terminal of Human EPHB2.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EPH Receptor B2 (EPHB2)

    别名

    EPHB2

    背景

    Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. Beside axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.

    Kiyokawa E., Cancer Res. 54:3645-3650(1994).
    Ikegaki N., Hum. Mol. Genet. 4:2033-2045(1995).
    Tang X.X., Oncogene 17:521-526(1998).

    Aliases: cek5 antibody, Developmentally regulated EPH related tyrosine kinase antibody, DRT antibody, EK5 antibody, ELK related protein tyrosine kinase antibody, Eph receptor B2 antibody, EPH tyrosine kinase 3 antibody, EPH-like kinase 5 antibody, EPHB2 antibody, EPHB2_HUMAN antibody, Ephrin type B receptor 2 antibody, Ephrin type-B receptor 2 antibody, EPHT 3 antibody, ERK antibody, ETECK antibody, hEK5 antibody, Nuk antibody, Prkm 5 antibody, Receptor protein tyrosine kinase HEK 5 antibody, Renal carcinoma antigen NY-REN-47 antibody, Sek 3 antibody, Tyro 5 antibody, Tyrosine protein kinase receptor CEK 5 antibody, Tyrosine protein kinase receptor EPH 3 antibody, Tyrosine protein kinase receptor QEK 5 antibody, Tyrosine-protein kinase receptor EPH-3 antibody, Tyrosine-protein kinase TYRO5 antibody

    UniProt

    P29323

    途径

    RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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