VAV1 抗体 (Tyr174)
Quick Overview for VAV1 抗体 (Tyr174) (ABIN7180104)
抗原
See all VAV1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Tyr174
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VAV1 (Vav 1 Oncogene (VAV1))
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别名
- VAV1
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背景
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Background: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Ana V. Miletic, J. Biol. Chem., Dec 2006, 281: 38257 - 38265.
Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003, 23: 6291 - 6299.
Vered Schapira, Cancer Res., Jun 2006, 66: 6183 - 6191.
Maya Groysman, J. Biol. Chem., Dec 2002, 277: 50121 - 50130.Aliases: Oncogene vav antibody, p95Vav antibody, Proto-oncogene vav antibody, Protooncogene vav antibody, VAV 1 antibody, VAV 1 oncogene antibody, VAV antibody, Vav proto oncogene antibody, VAV_HUMAN antibody, VAV1 antibody
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UniProt
- P15498
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
抗原
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