STAT5B 抗体 (Ser731)
Quick Overview for STAT5B 抗体 (Ser731) (ABIN7180086)
抗原
See all STAT5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser731
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).
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亚型
- IgG
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应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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别名
- STAT5B
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背景
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Background: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002, 72: 819.
Stanislaw M. Stepkowski, Blood, Jan 2002, 99: 680 - 689.
Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003, 14: 40.Aliases: Signal transducer and activator of transcription 5B antibody, STA5B_HUMAN antibody, STAT5 antibody, Stat5b antibody, Transcription factor STAT5B antibody
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UniProt
- P51692
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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