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c-FOS 抗体 (Thr232)

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7180011
发货至: 中国

Quick Overview for c-FOS 抗体 (Thr232) (ABIN7180011)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    Thr232

    交叉反应

    人, 小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human FOS around the phosphorylation site of threonine 232 (V-A-T(p)-P-E).

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    FOS

    背景

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    van Straaten F., Proc. Natl. Acad. Sci. U.S.A. 80:3183-3187(1983).
    Hai T., Genes Dev. 3:2083-2090(1989).
    Heilig R., Nature 421:601-607(2003).

    Aliases: Activator protein 1 antibody, AP 1 antibody, C FOS antibody, Cellular oncogene c fos antibody, Cellular oncogene fos antibody, FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody, FBJ murine osteosarcoma viral oncogene homolog antibody, FBJ murine osteosarcoma viral v fos oncogene homolog antibody, FBJ Osteosarcoma Virus antibody, FOS antibody, FOS protein antibody, FOS_HUMAN antibody, G0 G1 switch regulatory protein 7 antibody, G0/G1 switch regulatory protein 7 antibody, G0S7 antibody, Oncogene FOS antibody, p55 antibody, proto oncogene c Fos antibody, Proto oncogene protein c fos antibody, Proto-oncogene c-Fos antibody, v fos FBJ murine osteosarcoma viral oncogene homolog antibody

    UniProt

    P01100

    途径

    S100 Proteins
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