Cyclin D2 抗体 (Thr280)
Quick Overview for Cyclin D2 抗体 (Thr280) (ABIN7179999)
抗原
See all Cyclin D2 (CCND2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Thr280
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human Cyclin D2 around the phosphorylation site of threonine 280 (A-S-T(p)-P-T).
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亚型
- IgG
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anti-Cyclin D2 (CCND2) (AA 161-288) antibody
CCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 47-267) antibodyCCND2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 68-278) antibodyCCND2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 215-285) antibodyCCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) antibodyCCND2 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CCND2-2620 unconjugated
anti-Cyclin D2 (CCND2) (AA 190-289) antibodyCCND2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B10 unconjugated
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应用备注
- WB:1:500-1:3000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cyclin D2 (CCND2)
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别名
- CCND2
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背景
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Background: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex By similarity.
Xiong Y., Genomics 13:575-584(1992).
Palmero I., Oncogene 8:1049-1054(1993).
Kalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.Aliases: CCND 2 antibody, ccnd2 antibody, CCND2_HUMAN antibody, CyclinD2 antibody, G1/S specific cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, KIAK0002 antibody, MGC102758 antibody, MPPH3 antibody
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UniProt
- P30279
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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