APLF 抗体 (Ser116)
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北京 101111
Quick Overview for APLF 抗体 (Ser116) (ABIN7179974)
抗原
See all APLF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser116
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原理
- APLF (Ab-116) Antibody
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交叉反应
- 小鼠
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized non-phosphopeptide derived from Human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V).
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亚型
- IgG
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anti-Aprataxin and PNKP Like Factor (APLF) (Ser116) antibody
APLF 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin and PNKP Like Factor (APLF) (Internal Region) antibodyAPLF 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin and PNKP Like Factor (APLF) (AA 200-380) antibodyAPLF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin and PNKP Like Factor (APLF) (Tyr861) antibodyAPLF 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin and PNKP Like Factor (APLF) (AA 82-131) antibodyAPLF 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APLF (Aprataxin and PNKP Like Factor (APLF))
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别名
- APLF
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背景
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Background: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Saunders W.S., J. Cell Sci. 104:573-582(1993).
Ye Q., J. Biol. Chem. 271:14653-14656(1996).
Ye Q., J. Biol. Chem. 272:14983-14989(1997).Aliases: 2010301N04Rik antibody, AI452191 antibody, Aplf antibody, APLF_HUMAN antibody, Aprataxin and PNK-like factor antibody, Apurinic-apyrimidinic endonuclease APLF antibody, C2orf13 antibody, PNK and APTX like FHA protein antibody, PNK and APTX-like FHA domain-containing protein antibody, RGD1565557 antibody, XIP1 antibody, XRCC1 interacting protein 1 antibody, XRCC1-interacting protein 1 antibody
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UniProt
- Q8IW19
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途径
- DNA Damage Repair
抗原
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