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Ephrin A5 抗体 (AA 21-203) (FITC)

EFNA5 适用: 大鼠 宿主: 兔 Polyclonal FITC
产品编号 ABIN7178847
发货至: 中国
  • 抗原 See all Ephrin A5 (EFNA5) 抗体
    Ephrin A5 (EFNA5)
    抗原表位
    • 15
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-203
    适用
    • 42
    • 35
    • 25
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 43
    • 5
    克隆类型
    • 44
    • 4
    多克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ephrin A5 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Rat Ephrin-A5 protein (21-203AA)
    亚型
    IgG
    Top Product
    Discover our top product EFNA5 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Ephrin A5 (EFNA5)
    别名
    Efna5 (EFNA5 产品)
    别名
    EFNA5 antibody, af1 antibody, efl5 antibody, rags antibody, eplg7 antibody, lerk7 antibody, AL-1 antibody, AV158822 antibody, EFL-5 antibody, Ephrin-A5 antibody, Epl7 antibody, LERK-7 antibody, RAGS antibody, Lerk7 antibody, AF1 antibody, EFL5 antibody, EPLG7 antibody, GLC1M antibody, LERK7 antibody, ephrin A5 antibody, EFNA5 antibody, efna5 antibody, Efna5 antibody
    背景

    Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion

    Aliases: Efna5 antibody, Eplg7 antibody, Lerk7 antibody, Ephrin-A5 antibody, AL-1 antibody, EPH-related receptor tyrosine kinase ligand 7 antibody, LERK-7 antibody

    UniProt
    P97605
    途径
    RTK signaling
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