IL-7 抗体
Quick Overview for IL-7 抗体 (ABIN7178671)
抗原
See all IL-7 (IL7) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of Human IL7
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亚型
- IgG
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应用备注
- WB:1:500-1:2000, IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IL-7 (IL7) (Interleukin 7 (IL7))
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别名
- IL7
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背景
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Background: IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis. Stromal and epithelial cells within the bone marrow and thymus produce IL-7. The primary targets of IL-7 are T cells, B cells, and dendritic cells. IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling. While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear. In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naïve and memory αβ T cells, as well as γδ T cells. The IL-7 receptor is a heterodimer of the common γ chain, γc, and the IL-7-specific IL-7Rα. IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5.
Aliases: IL 7 antibody; IL-7 antibody; Il7 antibody; IL7_HUMAN antibody; Interleukin 7 antibody; Interleukin-7 antibody; LP-1 antibody; Lymphopoietin 1 antibody
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UniProt
- P13232
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途径
- JAK/STAT Signaling
抗原
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