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IL-7 抗体

The 兔 多克隆 anti-IL-7 antibody (ABIN7178671) specifically detects IL-7 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7178671
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-7 抗体 (ABIN7178671)

抗原

See all IL-7 (IL7) 抗体
IL-7 (IL7) (Interleukin 7 (IL7))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 原理

    IL7 Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of Human IL7

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IL-7 (IL7) (Interleukin 7 (IL7))

    别名

    IL7

    背景

    Background: IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis. Stromal and epithelial cells within the bone marrow and thymus produce IL-7. The primary targets of IL-7 are T cells, B cells, and dendritic cells. IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling. While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear. In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naïve and memory αβ T cells, as well as γδ T cells. The IL-7 receptor is a heterodimer of the common γ chain, γc, and the IL-7-specific IL-7Rα. IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5.

    Aliases: IL 7 antibody; IL-7 antibody; Il7 antibody; IL7_HUMAN antibody; Interleukin 7 antibody; Interleukin-7 antibody; LP-1 antibody; Lymphopoietin 1 antibody

    UniProt

    P13232

    途径

    JAK/STAT Signaling
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