CD11b 抗体 (FITC)
Quick Overview for CD11b 抗体 (FITC) (ABIN7178495)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant Protein
-
亚型
- IgG1, IgG1 kappa
-
-
-
-
应用备注
- Recommended dilution:IF:1:100-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
别名
- ITGAM
-
背景
-
Background: 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690
Aliases: N/A
-
UniProt
- P11215
-
途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
-