CD163 抗体 (AA 86-365) (FITC)
Quick Overview for CD163 抗体 (AA 86-365) (FITC) (ABIN7177828)
抗原
See all CD163 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-365
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交叉反应
- 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD163
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别名
- Cd163
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背景
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Background: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
Aliases: Cd163 antibody, M130Scavenger receptor cysteine-rich type 1 protein M130 antibody, CD antigen CD163) [Cleaved into: Soluble CD163 antibody, sCD163)] antibody
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UniProt
- Q2VLH6
抗原
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