Perforin 1 抗体 (AA 21-554)
Quick Overview for Perforin 1 抗体 (AA 21-554) (ABIN7177734)
抗原
See all Perforin 1 (PRF1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 21-554
-
交叉反应
- 人, 小鼠
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Mouse Perforin-1 protein (21-554AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
-
别名
- Prf1
-
背景
-
Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Aliases: Prf1 antibody, Pfp antibody, Perforin-1 antibody, P1 antibody, Cytolysin antibody, Lymphocyte pore-forming protein antibody
-
UniProt
- P10820
-
途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
-