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SNAIL 抗体 (AA 1-264) (HRP)

This HRP-conjugated 兔 多克隆 anti-SNAIL antibody specifically detects SNAIL in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7176603
发货至: 中国
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Quick Overview for SNAIL 抗体 (AA 1-264) (HRP) (ABIN7176603)

抗原

See all SNAIL (SNAI1) 抗体
SNAIL (SNAI1)

适用

  • 84
  • 40
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宿主

  • 70
  • 12
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克隆类型

  • 75
  • 12
多克隆

标记

  • 64
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This SNAIL antibody is conjugated to HRP

应用范围

  • 65
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  • 32
  • 21
  • 12
  • 5
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  • 3
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  • 1
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ELISA
  • 抗原表位

    • 14
    • 11
    • 9
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    • 4
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    • 2
    • 2
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    • 2
    • 2
    • 1
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    AA 1-264

    原理

    SNAI1 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Zinc finger protein SNAI1 protein (1-264AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SNAIL (SNAI1)

    别名

    SNAI1

    背景

    Background: Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5\'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.

    Aliases: dJ710H13.1 antibody, Protein sna antibody, Protein snail homolog 1 antibody, Protein snail homolog antibody, SLUGH2 antibody, SNA antibody, Sna protein antibody, SNAH antibody, SNAI antibody, snai1 antibody, SNAI1_HUMAN antibody, Snail 1 homolog antibody, Snail 1 zinc finger protein antibody, SNAIL antibody, Snail family transcriptional repressor 1 antibody, Snail homolog 1 (Drosophila) antibody, SNAIL, Drosophila, homolog of, 1 antibody, SNAIL1 antibody, Zinc finger protein SNAI1 antibody

    UniProt

    O95863

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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