TRIM27 抗体 (AA 214-513)
Quick Overview for TRIM27 抗体 (AA 214-513) (ABIN7176599)
抗原
See all TRIM27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 214-513
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Zinc finger protein RFP protein (214-513AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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别名
- TRIM27
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背景
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of \\\'Lys-48\\\'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of \\\'Lys-63\\\'-linked polyubiquitin chains at \\\'Lys-220\\\' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.
Aliases: AW538890 antibody, DAAP-182E11.3 antibody, MGC189472 antibody, OTTHUMP00000029314 antibody, Ret finger protein antibody, RFP antibody, RFP transforming protein antibody, Rfp1 antibody, RING finger protein 76 antibody, RNF76 antibody, TRI27_HUMAN antibody, TRIM 27 antibody, Trim27 antibody, Tripartite motif containing 27 antibody, Tripartite motif containing protein 27 antibody, Tripartite motif protein TRIM27 antibody, Tripartite motif-containing protein 27 antibody, Zinc finger protein RFP antibody
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UniProt
- P14373
抗原
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