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TRIM27 抗体 (AA 214-513)

This anti-TRIM27 antibody is a 兔 多克隆 antibody detecting TRIM27 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7176599
发货至: 中国

Quick Overview for TRIM27 抗体 (AA 214-513) (ABIN7176599)

抗原

See all TRIM27 抗体
TRIM27 (Tripartite Motif Containing 27 (TRIM27))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRIM27 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 214-513

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Zinc finger protein RFP protein (214-513AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRIM27 (Tripartite Motif Containing 27 (TRIM27))

    别名

    TRIM27

    背景

    Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of \\\'Lys-48\\\'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of \\\'Lys-63\\\'-linked polyubiquitin chains at \\\'Lys-220\\\' of WASH1, leading to promote endosomal F-actin assembly (PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.

    Aliases: AW538890 antibody, DAAP-182E11.3 antibody, MGC189472 antibody, OTTHUMP00000029314 antibody, Ret finger protein antibody, RFP antibody, RFP transforming protein antibody, Rfp1 antibody, RING finger protein 76 antibody, RNF76 antibody, TRI27_HUMAN antibody, TRIM 27 antibody, Trim27 antibody, Tripartite motif containing 27 antibody, Tripartite motif containing protein 27 antibody, Tripartite motif protein TRIM27 antibody, Tripartite motif-containing protein 27 antibody, Zinc finger protein RFP antibody

    UniProt

    P14373
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