TRIM27 抗体
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北京 101111
Quick Overview for TRIM27 抗体 (ABIN7126897)
抗原
See all TRIM27 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TRIM27 Antibody
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特异性
- Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.
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交叉反应 (详细)
- Human. Predicted to react with Mouse and Rat.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human TRIM27 protein
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亚型
- IgG2a
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or Raji cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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别名
- TRIM27
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背景
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AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP
HeLa, U87 or Raji cells.
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分子量
- 58.49kDa
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基因ID
- 5987, 440382
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UniProt
- P14373
抗原
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