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UBE2S 抗体 (AA 1-222)

This 兔 多克隆 antibody specifically detects UBE2S in IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7174484
发货至: 中国
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Quick Overview for UBE2S 抗体 (AA 1-222) (ABIN7174484)

抗原

See all UBE2S 抗体
UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

适用

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宿主

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克隆类型

  • 74
  • 9
多克隆

标记

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This UBE2S antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 8
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    AA 1-222

    原理

    UBE2S Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Ubiquitin-conjugating enzyme E2 S protein (1-222AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    UBE2S (Ubiquitin-Conjugating Enzyme E2S (UBE2S))

    别名

    UBE2S

    背景

    Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes \\\'Lys-11\\\'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating \\\'Lys-11\\\'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro, it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except \\\'Lys-48\\\'-linked polyubiquitination.

    Aliases: AA409170 antibody, E2 EPF antibody, E2-EPF antibody, E2EPF antibody, EPF5 antibody, MGC101982 antibody, Ube2s antibody, UBE2S_HUMAN antibody, Ubiquitin carrier protein S antibody, Ubiquitin conjugating enzyme E2 24 kD antibody, Ubiquitin conjugating enzyme E2 24 kDa antibody, Ubiquitin conjugating enzyme E2 EPF5 antibody, Ubiquitin conjugating enzyme E2 S antibody, Ubiquitin conjugating enzyme E2S antibody, Ubiquitin protein ligase S antibody, Ubiquitin-conjugating enzyme E2 S antibody, Ubiquitin-conjugating enzyme E2-24 kDa antibody, Ubiquitin-conjugating enzyme E2-EPF5 antibody, Ubiquitin-protein ligase S antibody

    UniProt

    Q16763

    途径

    Ubiquitin Proteasome Pathway
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