UBE2N 抗体 (AA 20-138) (Biotin)
Quick Overview for UBE2N 抗体 (AA 20-138) (Biotin) (ABIN7174473)
抗原
See all UBE2N 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-138
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin-conjugating enzyme E2 N protein (20-138AA)
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibody
UBE2N 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1-D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) antibodyUBE2N 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 41-74) antibodyUBE2N 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB49505 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 56-152) antibodyUBE2N 适用: 大鼠, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 20-138) antibodyUBE2N 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C11-G11 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (C-Term) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 绵羊, 兔, 马, 豚鼠, Drosophila melanogaster, 小鸡, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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别名
- UBE2N
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背景
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Background: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical \'Lys-63\'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the \'Lys-63\'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the \'Lys-63\'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate \'Lys-63\'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes.
Aliases: Bendless like ubiquitin conjugating enzyme antibody, Bendless-like ubiquitin-conjugating enzyme antibody, BLU antibody, EC 6.3.2.19 antibody, Epididymis secretory protein Li 71 antibody, HEL-S-71 antibody, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds antibody, MGC131857 antibody, MGC8489 antibody, UBC 13 antibody, Ubc13 antibody, UbCH ben antibody, UbcH-ben antibody, UbcH13 antibody, UBCHBEN antibody, Ube 2N antibody, Ube2n antibody, UBE2N_HUMAN antibody, Ubiquitin carrier protein N antibody, Ubiquitin conjugating enzyme E2 N antibody, Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13) antibody, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast) antibody, Ubiquitin conjugating enzyme E2N antibody, Ubiquitin protein ligase N antibody, Ubiquitin-conjugating enzyme E2 N antibody, Ubiquitin-protein ligase N antibody, Yeast UBC13 homolog antibody
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UniProt
- P61088
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
抗原
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