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- 抗原 See all UBE2N 抗体
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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抗原表位
- AA 41-74
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2N antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This UBE2N antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-74 amino acids from the Central region of human UBE2N.
- 克隆位点
- RB49505
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UBE2N Primary Antibody
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anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibody
UBE2N 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1-D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) antibodyUBE2N 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 兔, 绵羊, Saccharomyces cerevisiae, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 兔, 绵羊, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 56-152) antibodyUBE2N 适用: 大鼠, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 20-138) antibodyUBE2N 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C11-G11 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (C-Term) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔, 绵羊, Drosophila melanogaster, 小鸡, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 80-129) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 兔, 绵羊, Drosophila melanogaster, 小鸡, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:500. WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
- 别名
- UBE2N (UBE2N 产品)
- 别名
- UBC13 antibody, UbcH-ben antibody, UbcH13 antibody, 1500026J17Rik antibody, AL022654 antibody, BB101821 antibody, ube2n antibody, wu:fb11b03 antibody, wu:fc08b06 antibody, zgc:55726 antibody, ubc13 antibody, ubch-ben antibody, UBE2N antibody, ube2nl antibody, zgc:63901 antibody, ubiquitin conjugating enzyme E2 N antibody, ubiquitin-conjugating enzyme E2N antibody, ubiquitin conjugating enzyme E2 N S homeolog antibody, ubiquitin-conjugating enzyme E2Na antibody, ubiquitin-conjugating enzyme E2Nb antibody, UBE2N antibody, Ube2n antibody, ube2n.S antibody, ube2na antibody, LOC100533434 antibody, ube2n antibody, ube2nb antibody
- 背景
- The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes (By similarity).
- 分子量
- 17138
- UniProt
- P61088
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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