UBASH3A 抗体 (AA 287-455)
Quick Overview for UBASH3A 抗体 (AA 287-455) (ABIN7174413)
抗原
See all UBASH3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 287-455
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
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别名
- UBASH3A
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背景
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Background: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH . May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Aliases: Cbl interacting protein 4 antibody, Cbl-interacting protein 4 antibody, CLIP4 antibody, STS 2 antibody, STS-2 antibody, Suppressor of T cell receptor signaling 2 antibody, Suppressor of T-cell receptor signaling 2 antibody, T cell ubiquitin ligand antibody, T cell ubiquitin ligand protein antibody, T-cell ubiquitin ligand 1 antibody, TULA antibody, TULA-1 antibody, UBASH3A antibody, ubiquitin associated and SH3 domain containing, A antibody, Ubiquitin-associated and SH3 domain-containing protein A antibody, UBS3A_HUMAN antibody
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UniProt
- P57075
抗原
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