BAP1 抗体 (AA 460-729)
Quick Overview for BAP1 抗体 (AA 460-729) (ABIN7174361)
抗原
See all BAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 460-729
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase BAP1 protein (460-729AA)
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亚型
- IgG
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anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 36-66) antibody
BAP1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB4559-4560 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 460-729) antibodyBAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (pSer592) antibodyBAP1 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 1-729) antibodyBAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 191-326) antibodyBAP1 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal BAP1-2431 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) (AA 36-66) antibodyBAP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibodyBAP1 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal BP-1 unconjugated
anti-BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1) antibody (Magnetic Particles)BAP1 适用: 人 IP 宿主: 小鼠 Monoclonal BP-1 Magnetic Particles
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应用备注
- Recommended dilution: WB:1:200-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
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别名
- BAP1
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背景
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Background: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at \\\'Lys-119\\\' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward \\\'Lys-48\\\'-linked polyubiquitin chains compared to \\\'Lys-63\\\'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
Aliases: BAP 1 antibody, Bap1 antibody, BAP1_HUMAN antibody, BRCA 1 associated protein 1 antibody, BRCA1 associated protein 1 antibody, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody, BRCA1-associated protein 1 antibody, Cerebral protein 13 antibody, Cerebral protein 6 antibody, DKFZp686N04275 antibody, FLJ35406 antibody, FLJ37180 antibody, HUCEP 13 antibody, Hucep 6 antibody, HUCEP13 antibody, Hucep6 antibody, KIAA0272 antibody, TPDS antibody, Ubiquitin carboxy terminal hydrolase antibody, Ubiquitin carboxyl terminal hydrolase BAP 1 antibody, Ubiquitin carboxyl terminal hydrolase BAP1 antibody, Ubiquitin carboxyl-terminal hydrolase BAP1 antibody, UCHL2 antibody
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UniProt
- Q92560
抗原
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