USP8 抗体 (C-Term)
Quick Overview for USP8 抗体 (C-Term) (ABIN7174360)
抗原
See all USP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-270, C-Term
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 8 protein (1-270AA)
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 8 (USP8) antibody
USP8 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 1-270) antibodyUSP8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 861-910) antibodyUSP8 适用: 人, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 151-200) antibodyUSP8 适用: 人, Pig, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 777-1118) antibodyUSP8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 1058-1087), (C-Term) antibodyUSP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04288 unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (C-Term) antibodyUSP8 适用: 人, 小鼠, Pig, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (C-Term) antibodyUSP8 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
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别名
- USP8
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背景
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Background: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both \\\'Lys-48\\\' an \\\'Lys-63\\\'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.
Aliases: Deubiquitinating enzyme 8 antibody, FLJ34456 antibody, hUBPy antibody, HumORF8 antibody, KIAA0055 antibody, MGC129718 antibody, SPG59 antibody, Ubiquitin carboxyl-terminal hydrolase 8 antibody, Ubiquitin isopeptidase Y antibody, ubiquitin specific peptidase 8 antibody, Ubiquitin thioesterase 8 antibody, Ubiquitin-specific-processing protease 8 antibody, UBP8_HUMAN antibody, UBPY antibody, Usp8 antibody
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UniProt
- P40818
抗原
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