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USP5 抗体 (AA 201-500)

This anti-USP5 antibody is a 兔 多克隆 antibody detecting USP5 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7174348
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for USP5 抗体 (AA 201-500) (ABIN7174348)

抗原

See all USP5 抗体
USP5 (Ubiquitin Specific Peptidase 5 (USP5))

适用

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宿主

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克隆类型

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多克隆

标记

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This USP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 201-500

    原理

    USP5 Antibody

    交叉反应

    小鼠

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    USP5 (Ubiquitin Specific Peptidase 5 (USP5))

    别名

    USP5

    背景

    Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \\\'Lys-48\\\'-linked polyubiquitin disassembly. Binds linear and \\\'Lys-63\\\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    Aliases: Deubiquitinating enzyme 5 antibody, Isopeptidase T antibody, ISOT 1 antibody, ISOT antibody, Ubiquitin carboxyl-terminal hydrolase 5 antibody, Ubiquitin isopeptidase T antibody, Ubiquitin specific peptidase 5 (isopeptidase T) antibody, Ubiquitin specific peptidase 5 antibody, Ubiquitin specific processing protease 5 antibody, Ubiquitin specific protease 5 (isopeptidase T) antibody, Ubiquitin specific protease 5 (ubiquitin isopeptidase T) antibody, Ubiquitin thioesterase 5 antibody, Ubiquitin thiolesterase 5 antibody, Ubiquitin-specific-processing protease 5 antibody, UBP5_HUMAN antibody, Usp5 antibody

    UniProt

    P45974
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