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USP37 抗体 (AA 671-797)

This anti-USP37 antibody is a 兔 多克隆 antibody detecting USP37 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7174324
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for USP37 抗体 (AA 671-797) (ABIN7174324)

抗原

See all USP37 抗体
USP37 (Ubiquitin Specific Peptidase 37 (USP37))

适用

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宿主

  • 32

克隆类型

  • 32
多克隆

标记

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This USP37 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 671-797

    原理

    USP37 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 37 protein (671-797AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    USP37 (Ubiquitin Specific Peptidase 37 (USP37))

    别名

    USP37

    背景

    Background: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of \\\'Lys-11\\\'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of \\\'Lys-48\\\'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).

    Aliases: Deubiquitinating enzyme 3 antibody, Deubiquitinating enzyme 37 antibody, EC 3.1.2.15 antibody, KIAA1594 antibody, MGC117261 antibody, OTTHUMP00000164146 antibody, tmp_locus_50 antibody, Ubiquitin carboxyl-terminal hydrolase 37 antibody, Ubiquitin specific peptidase 37 antibody, Ubiquitin specific processing protease 37 antibody, Ubiquitin specific protease 37 antibody, Ubiquitin thioesterase 37 antibody, Ubiquitin thiolesterase 37 antibody, Ubiquitin-specific-processing protease 37 antibody, UBP37_HUMAN antibody, USP37 antibody

    UniProt

    Q86T82
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