USP14 抗体 (C-Term)
Quick Overview for USP14 抗体 (C-Term) (ABIN7174258)
抗原
See all USP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-494, C-Term
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 protein (1-494AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
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别名
- USP14
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背景
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Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Aliases: Deubiquitinating enzyme 14 antibody, TGT antibody, tRNA guanine transglycosylase 60 kD subunit antibody, tRNA guanine transglycosylase antibody, Ubiquitin carboxyl terminal hydrolase 14 antibody, Ubiquitin carboxyl-terminal hydrolase 14 antibody, Ubiquitin specific peptidase 14 antibody, Ubiquitin specific processing protease 14 antibody, Ubiquitin specific protease 14 antibody, Ubiquitin thiolesterase 14 antibody, Ubiquitin-specific-processing protease 14 antibody, UBP14_HUMAN antibody, USP 14 antibody, USP14 antibody
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UniProt
- P54578
抗原
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