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TDP1 抗体 (AA 1-260)

The 兔 多克隆 anti-TDP1 antibody (ABIN7174129) specifically detects TDP1 in WB, ELISA, IHC 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7174129
发货至: 中国
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Quick Overview for TDP1 抗体 (AA 1-260) (ABIN7174129)

抗原

See all TDP1 抗体
TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TDP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
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    AA 1-260

    原理

    TDP1 Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

    别名

    TDP1

    背景

    Background: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3\\\'-phosphodiester bond, giving rise to DNA with a free 3\\\' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3\\\'-phosphoglycolates on protruding 3\\\' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3\\\'exonuclease activity and can remove a single nucleoside from the 3\\\'end of DNA and RNA molecules with 3\\\'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3\\\'phosphate.

    Aliases: AI838772 antibody, AW493413 antibody, FLJ11090 antibody, MGC104252 antibody, MGC112732 antibody, RP24-311F12.2 antibody, SCAN1 antibody, TDP1 antibody, TYDP antibody, TYDP1_HUMAN antibody, Tyr-DNA phosphodiesterase 1 antibody, Tyrosyl-DNA phosphodiesterase 1 antibody

    UniProt

    Q9NUW8
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