TWIST1 抗体 (AA 1-80)
Quick Overview for TWIST1 抗体 (AA 1-80) (ABIN7173945)
抗原
See all TWIST1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Twist-related protein 1 protein (1-80AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))
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别名
- TWIST1
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背景
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Background: Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
Aliases: ACS3 antibody, B-HLH DNA binding protein antibody, bHLHa38 antibody, BPES2 antibody, BPES3 antibody, Class A basic helix-loop-helix protein 38 antibody, CRS antibody, CRS1 antibody, CSO antibody, H-twist antibody, OTTHUMP00000116043 antibody, SCS antibody, Twist basic helix loop helix transcription factor 1 antibody, Twist family bHLH transcription factor 1 antibody, Twist homolog 1 (Drosophila) antibody, Twist homolog 1 antibody, TWIST homolog of drosophila antibody, Twist related protein 1 antibody, Twist-related protein 1 antibody, TWIST1 antibody, TWST1_HUMAN antibody
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UniProt
- Q15672
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途径
- p53 Pathway, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity
抗原
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