TSEN15 抗体 (AA 1-171) (HRP)
Quick Overview for TSEN15 抗体 (AA 1-171) (HRP) (ABIN7173539)
抗原
See all TSEN15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-171
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human tRNA-splicing endonuclease subunit Sen15 protein (1-171AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))
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别名
- TSEN15
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背景
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Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5\' and 3\' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2\',3\' cyclic phosphate and 5\'-OH termini (PubMed:15109492, PubMed:27392077). There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3\'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3\'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (PubMed:15109492).
Aliases: TSEN15 antibody, C1orf19 antibody, SEN15 antibody, tRNA-splicing endonuclease subunit Sen15 antibody, SEN15 homolog antibody, HsSEN15 antibody, tRNA-intron endonuclease Sen15 antibody
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UniProt
- Q8WW01
抗原
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