TSEN15 抗体 (C-Term)
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北京 101111
Quick Overview for TSEN15 抗体 (C-Term) (ABIN2784943)
抗原
See all TSEN15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Tsen15 Antibody - C-terminal region
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序列
- ASLSHNRIRE ILKASRKLQG DPELPMSFTL AIVESDSTIV YYKLTDGFML
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Tsen15. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52469-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))
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别名
- Tsen15
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背景
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Targeted Subunit: Sen15
Background Information: Tsen15 is a non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Gene Name: TRNA splicing endonuclease 15 homolog (S. cerevisiae)
Alternative Symbols: Sen15, AL023077, 5730449L18Rik
Protein Name: tRNA-splicing endonuclease subunit Sen15
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分子量
- 18kDa
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基因ID
- 66637
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NCBI登录号
- NP_079953
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UniProt
- Q8R3W5
抗原
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