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TSEN15 抗体 (AA 1-171) (Biotin)

The 兔 多克隆 anti-TSEN15 antibody is suitable to detect TSEN15 in samples from 人. It has been validated for ELISA.
产品编号 ABIN7173537
发货至: 中国
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Quick Overview for TSEN15 抗体 (AA 1-171) (Biotin) (ABIN7173537)

抗原

See all TSEN15 抗体
TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

适用

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宿主

  • 14
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克隆类型

  • 15
  • 2
多克隆

标记

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This TSEN15 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

    • 4
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    • 1
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    AA 1-171

    原理

    TSEN15 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human tRNA-splicing endonuclease subunit Sen15 protein (1-171AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

    别名

    TSEN15

    背景

    Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5\' and 3\' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2\',3\' cyclic phosphate and 5\'-OH termini (PubMed:15109492, PubMed:27392077). There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3\'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3\'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (PubMed:15109492).

    Aliases: TSEN15 antibody, C1orf19 antibody, SEN15 antibody, tRNA-splicing endonuclease subunit Sen15 antibody, SEN15 homolog antibody, HsSEN15 antibody, tRNA-intron endonuclease Sen15 antibody

    UniProt

    Q8WW01
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