TMEM59 抗体 (AA 59-201) (HRP)
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Quick Overview for TMEM59 抗体 (AA 59-201) (HRP) (ABIN7173248)
抗原
See all TMEM59 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-201
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原理
- TMEM59 Antibody, HRP conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Transmembrane protein 59 protein (59-201AA)
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亚型
- IgG
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anti-Transmembrane Protein 59 (TMEM59) antibody
TMEM59 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 59-201) antibodyTMEM59 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TMEM59 (Transmembrane Protein 59 (TMEM59))
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别名
- TMEM59
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背景
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Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).
Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody
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UniProt
- Q9BXS4
抗原
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