TGFB3 抗体 (AA 301-412)
Quick Overview for TGFB3 抗体 (AA 301-412) (ABIN7172834)
抗原
See all TGFB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-412
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Transforming growth factor beta-3 proprotein protein (301-412AA)
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亚型
- IgG
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anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibody
TGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) antibodyTGFB3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 298-409) antibodyTGFB3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (C-Term) antibodyTGFB3 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 274-372) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 215-249) antibodyTGFB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53679 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) antibody (Biotin)TGFB3 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Transforming Growth Factor, beta 3 (TGFB3) antibody (HRP)TGFB3 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
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应用备注
- Recommended dilution: IHC:1:50-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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别名
- TGFB3
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背景
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Background: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.Latency-associated peptide: Required to maintain the Transforming growth factor beta-3 (TGF-beta-3) chain in a latent state during storage in extracellular matrix (By similarity). Associates non-covalently with TGF-beta-3 and regulates its activation via interaction with \\\'milieu molecules\\\', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-3 (By similarity). Interaction with integrins results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-3.Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains remain non-covalently linked rendering TGF-beta-3 inactive during storage in extracellular matrix (By similarity). At the same time, LAP chain interacts with \\\'milieu molecules\\\', such as LTBP1 and LRRC32/GARP that control activation of TGF-beta-3 and maintain it in a latent state during storage in extracellular milieus (By similarity). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3 (By similarity). Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity).
Aliases: ARVD antibody, ARVD1 antibody, FLJ16571 antibody, LDS5 antibody, MGC105479 antibody, MGC118722 antibody, prepro-transforming growth factor beta-3 antibody, RNHF antibody, TGF beta 3 antibody, TGF beta3 antibody, TGF-beta-3 antibody, TGFB 3 antibody, Tgfb3 antibody, TGFB3_HUMAN antibody, transforming growth factor beta 3 antibody, Transforming growth factor beta-3 antibody
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UniProt
- P10600
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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