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LRRC32 抗体 (AA 301-500) (HRP)

This anti-LRRC32 antibody is a 兔 多克隆 antibody detecting LRRC32 in ELISA. Suitable for 人.
产品编号 ABIN7172810
发货至: 中国

Quick Overview for LRRC32 抗体 (AA 301-500) (HRP) (ABIN7172810)

抗原

See all LRRC32 抗体
LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

适用

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宿主

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克隆类型

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多克隆

标记

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This LRRC32 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 301-500

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

    别名

    LRRC32

    背景

    Background: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).

    Aliases: D11S833E antibody, GARP antibody, Garpin antibody, Glycoprotein A repetitions predominant antibody, Leucine rich repeat containing 32 antibody, Leucine-rich repeat-containing protein 32 antibody, LRC32_HUMAN antibody, LRRC32 antibody

    UniProt

    Q14392

    途径

    Activated T Cell Proliferation
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