LRRC32 抗体 (AA 301-500) (HRP)
Quick Overview for LRRC32 抗体 (AA 301-500) (HRP) (ABIN7172810)
抗原
See all LRRC32 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 301-500
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                                            交叉反应
- 人
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                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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                                            别名
- LRRC32
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                                            背景
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                        Background: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity). Aliases: D11S833E antibody, GARP antibody, Garpin antibody, Glycoprotein A repetitions predominant antibody, Leucine rich repeat containing 32 antibody, Leucine-rich repeat-containing protein 32 antibody, LRC32_HUMAN antibody, LRRC32 antibody 
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                                            UniProt
- Q14392
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                                            途径
- Activated T Cell Proliferation
 抗原
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