ZBTB33 抗体 (AA 113-228) (HRP)
Quick Overview for ZBTB33 抗体 (AA 113-228) (HRP) (ABIN7172778)
抗原
See all ZBTB33 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 113-228
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Transcriptional regulator Kaiso protein (113-228AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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别名
- ZBTB33
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背景
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Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5\'-CGCG-3\' and also binds to the non-methylated consensus sequence 5\'-CTGCNA-3\' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).
Aliases: Kaiso antibody, Kaiso protein antibody, Kaiso transcription factor antibody, KAISO_HUMAN antibody, Transcriptional regulator Kaiso antibody, ZBTB 33 antibody, Zbtb33 antibody, Zinc finger and BTB domain containing 33 antibody, Zinc finger and BTB domain-containing protein 33 antibody, Zinc finger transcription factor Kaiso antibody, ZNF 348 antibody, ZNF Kaiso antibody, ZNF348 antibody
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UniProt
- Q86T24
抗原
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