TFEB 抗体 (AA 1-476) (HRP)
Quick Overview for TFEB 抗体 (AA 1-476) (HRP) (ABIN7172539)
抗原
See all TFEB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-476
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Transcription factor EB protein (1-476AA)
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亚型
- IgG
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anti-Transcription Factor EB (TFEB) (AA 1-476) antibody
TFEB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Transcription Factor EB (TFEB) (Middle Region) antibodyTFEB 适用: 人, Cow, 犬, 马, 山羊, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-220) antibodyTFEB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (Internal Region) antibodyVerified TFEB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) antibodyTFEB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TFEB (Transcription Factor EB (TFEB))
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别名
- TFEB
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背景
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Background: Transcription factor that specifically recognizes and binds E-box sequences (5\'-CANNTG-3\'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5\'-GTCACGTGAC-3\') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
Aliases: Alpha TFEB antibody, AlphaTFEB antibody, bHLHe35 antibody, Class E basic helix-loop-helix protein 35 antibody, T cell transcription factor EB antibody, TCFEB antibody, TFEB antibody, TFEB_HUMAN antibody, Transcription factor EB antibody
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UniProt
- P19484
抗原
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