TLR6 抗体 (AA 32-586) (FITC)
Quick Overview for TLR6 抗体 (AA 32-586) (FITC) (ABIN7172280)
抗原
See all TLR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-586
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Toll-like receptor 6 protein (32-586AA)
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亚型
- IgG
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anti-Toll-Like Receptor 6 (TLR6) (AA 301-400) antibody
TLR6 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 393-423) antibodyTLR6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 722-753) antibodyTLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 32-586) antibodyTLR6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 608-796) antibodyTLR6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 408-424) antibody (PE)TLR6 适用: 人 FACS 宿主: 小鼠 Monoclonal 86B1153-2 PE
anti-Toll-Like Receptor 6 (TLR6) (AA 32-200) antibodyTLR6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 1-30) antibodyTLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 人, 小鼠 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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别名
- TLR6
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背景
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Background: Participates in the innate immune response to bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2 (PubMed:11441107). In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
Aliases: CD286 antibody, CD286 antigen antibody, TLR 6 antibody, Tlr6 antibody, TLR6_HUMAN antibody, Toll like receptor 6 precursor antibody, Toll-like receptor 6 antibody
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UniProt
- Q9Y2C9
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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