TLR1 抗体 (AA 25-580) (FITC)
Quick Overview for TLR1 抗体 (AA 25-580) (FITC) (ABIN7172263)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 25-580
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Toll-like receptor 1 protein (25-580AA)
-
亚型
- IgG
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- TLR1 (Toll-Like Receptor 1 (TLR1))
-
别名
- TLR1
-
背景
-
Background: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Aliases: CD281 antibody, CD281 antigen antibody, KIAA0012 antibody, LPRS5 antibody, rsc786 antibody, TIL antibody, TIL. LPRS5 antibody, Tlr1 antibody, TLR1_HUMAN antibody, Toll (Drosophila) homolog antibody, Toll like receptor 1 antibody, Toll-like receptor 1 antibody, Toll/interleukin-1 receptor-like protein antibody
-
UniProt
- Q15399
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
-