TOLLIP 抗体 (AA 86-163) (HRP)
Quick Overview for TOLLIP 抗体 (AA 86-163) (HRP) (ABIN7172260)
抗原
See all TOLLIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-163
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Toll-interacting protein (86-163AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TOLLIP (Toll Interacting Protein (TOLLIP))
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别名
- TOLLIP
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背景
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Background: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Aliases: Adapter protein antibody, FLJ33531 antibody, IL 1RAcPIP antibody, IL1RAcPIP antibody, TOLIP antibody, TOLIP_HUMAN antibody, Toll interacting protein antibody, Toll-interacting protein antibody, tollip antibody
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UniProt
- Q9H0E2
抗原
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